COSSAC

Background
Patrick works as a clincal data administrator in the clinical group at University College London (UCL) Medical School based at the Royal Free Hospital (RFH). Patrick currently works with Vivek to acquire data at the weekly breast and cancer multidisciplinary meetings.

Patrick holds a PhD in Vascular Biology (Induction of Heme Oxygenase-1 by Nitroxly Anion (NO-))from UCL, an MSc in Toxicology from Imperial College and a BSc (Hons) in Biomedical Sciences from Kingston University.

Patrick has worked for Novartis Pharma in the field of xenotransplantation. In addition, he has undertaken two years postdoctoral research at UCL studying the effect of an endogenous inhibitor of nitric oxide (NO), i.e. asymmetric dimethylarginine (ADMA), in preeclampsia. He has also worked as a medical secretary at the National Hospital for Neurology and Neurosurgery (NHNN) in the Epilepsy Department.

Interests
Outside of work Patrick is a keen cyclist and has completed the London to Cambridge cycle four times. He is also a keen Formula 1 fan and have attended the British Grand Prix at Silverstone on two occasions. Other interests include cooking (especially Indian cuisine), travelling (Argentina, Uruguay, the Lake District, Sicily) and reading (in particular crime and thriller novels).

Publications
1. Clark JE et al Cardioprotective actions by a water-soluble carbon monoxide-releasing molecule. Circ. Res. 93, e2-e8 (2003).

2. Kaur H et al Interaction of bilirubin and biliverdin with reactive nitrogen species. FEBS Lett. 543, 113-119 (2003).

3. Naughton P et al Interaction of heme with nitroxyl or nitric oxide amplifies heme oxygenase-1 induction: involvement of the transcription factor Nrf2. Cell. Mol. Biol. (Noisy-le-grand) 48, 885-894 (2002).

4. Naughton P et al Induction of heme oxygenase-1 by nitrosative stress. A role for nitroxyl anion. J. Biol. Chem. 277, 40666-40674 (2002).

Email
patrick.naughton@ucl.ac.uk